Featuring a diverse array of model organisms and scientific techniques, Sirtuins: Methods and Protocolscollects detailed contributions from experts in the field addressing this vital family of genes. Opening with methods to generate sirtuin biology tools, the book continues by covering methods to identify sirtuin substrates, to measure sirtuin activity, and to study sirtuin biology. Written in the highly successfulMethods in Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and easy to use, Sirtuins: Methods and Protocolspresents detailed protocols for sirtuin research that can be followed directly or modified to investigate new areas of sirtuin biology. | Sirtuins by Matthew D. Hirschey, Hardcover | Indigo Chapters